S4 25 (Andarine) SARM
Description
What is S4 25 (Andarine)?
Andarine produces a hard, dry look at the end of a cut. It also has one of the harder side effect profiles here, so it is run at a modest dose in short blocks.
Also sold as andarine, S4 or S-4.
Andarine is one of the older SARMs and it produces a hard, dry look rather than size, which is why it sits in cutting phases. It binds the androgen receptor selectively in muscle and bone, and it clears quickly, so it is typically used in short blocks at the end of a cut rather than run for months.
S4 25 benefits
- Produces a hard, dry look with no water at all
- Preserves lean tissue through a deficit
- Noticeable improvement in vascularity and definition
- Short half-life, so it clears quickly if it does not suit you
- Useful in the final weeks of a cut rather than through a bulk
- 25mg tablets, which halve to the 12.5mg most people find tolerable
S4 25 dosage
- Starting dose
- 12.5mg per day, half a tablet
- Common range
- 25 to 50mg per day
- Timing
- Split across the day, or morning only
- Cycle length
- 6 to 8 weeks
- Post-cycle therapy
- Required, plan it before you start
- Half-life
- About 4 hours
Start at half a tablet. The side effects scale directly with dose, and 12.5mg is comfortable for many people where 50mg is not.
The half-life is short, so splitting the dose is common. Dosing in the morning only means the worst of the visual disturbance has passed by evening, which matters if you drive.
Package content
- Tablets
- 50 per box, as 2 strips of 25
- Strength
- 25mg andarine per tablet
- Andarine per box
- 1250mg
- Half-life
- About 4 hours
- Brand
- Deus Medical
At 25mg a day one box covers 50 days.
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Who is S4 25 for?
People in the last weeks of a cut who want hardness and dryness from a short, modest run.
It is a poor choice for bulking, since it does not add size. Ostarine is the gentler option for holding muscle through a cut.
How to use S4 25
Swallow with water, split across the day or taken in the morning only. Start at half a tablet and increase only if it suits you.
Frequently asked questions
Do SARMs really need PCT?
Yes. This is the single most repeated piece of bad advice about them, and it costs people months of feeling flat while they wait for something to recover on its own.
SARMs are selective, not non-suppressive. They act on the androgen receptor and your body responds by shutting down its own production. A SERM such as tamoxifen or clomiphene is what restarts it.
How do I keep the side effects manageable?
Keep the dose modest and the run short. Andarine’s side effects are clearly dose related, so 12.5mg is comfortable for a lot of people where 50mg is not.
Splitting the dose across the day, or taking it in the morning only, is what most people settle on. If it does not suit you at a low dose, it is not going to at a higher one.
How long can I run it?
Six to eight weeks, and shorter is common. Andarine is a finishing compound rather than something to build a whole cycle around.
The short half-life means it clears quickly if you decide it does not suit you, which is one of its practical advantages.
What is it best used for?
The last weeks of a cut, where hardness and dryness matter and you are not trying to add anything.
It is a poor choice for a bulk. Andarine does not add size and running it for that reason is how people conclude it does nothing.
Andarine or ostarine for a cut?
Ostarine if the goal is holding what you have built while calories are low. It is the gentler of the two and it is the one to start with.
Andarine if you are already lean and want hardness and dryness in the final weeks. They do different jobs and a lot of people run ostarine through the cut and add andarine at the end.
All products are supplied exclusively for research and evaluation purposes and are not positioned as medical treatments or health solutions.

/S4%2025%20(Andarine)/s4_25_andarine_sarm_2025_08.png)